We’re making biologics for advanced immunoassay that better portrait cell features. You can multiplex and repeat sample measurements but this will not improve your knowledge of individual targets. Our goal is to bring to the bench assay technology that operates on bulk samples but returns readouts that fully portrait targets at the cellular level. And to make it happen we have to establish a full platform of systematized biologics and methods for using them.

Expect to submerge into a world of system oriented synthetic biology. For us, integration of systems is important and hence so is communication. You will be asked to contribute in laying down new rules for sourcing niche work to meet systemwide goals.

You will work with a small group of synthetic biologists and systems engineers that have established many of the foundational principles and technologies. We look for unique talent to contribute to our already diverse creative culture. Financing is secured for up to four years so the technology is our primary focus. We’re currently located in Pilsen, which means a rich culture, accessible outdoors, Prague a short train ride away, and much of central Europe accessible for weekend trips.

Role

  • Apply rational protein engineering and directed evolution methods for functional optimization with the goal of improving expression, activity, and substrate specificity.
  • Propose protein structures that integrate enzymatic and regulatory functions in fusion recombinants.
  • Collaborate in making other chemical modifications for improved functionality.
  • Contribute in developing the current protein engineering platform employing automation, liquid handling, and microfluidic solutions.

Requirements

  • PhD candidate or equivalent.
  • Experience in functional enzyme expression in microbial hosts.
  • Experience in protein engineering or directed evolution.
  • Experience in modular protein design a plus.